Desiree: dose escalation of everolimus published


We are proud to inform you that our article A multicentre, randomised, double-blind, phase II study to evaluate the tolerability of an induction dose escalation of everolimus in patients with metastatic breast cancer (DESIREE; GBG 86) is now available online.


A dose-escalation schema of everolimus over 3 weeks can be successfully used to reduce the incidence of high-grade stomatitis in the first 12 weeks of treatment in patients with hormone receptor positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer.“