BMBC (GBG 79)

The BMBC (Brain Metastases in Breast Cancer Network Germany) registry study is intended to contribute to the prospective and retrospective collection of data on the course of disease in patients with brain metastases from breast cancer. In addition, scientific projects are planned to contribute to a better understanding of the causes of the development of brain metastases in breast cancer.

In the treatment of patients with breast cancer, the increasing incidence of brain metastases (>30%) is a growing problem, as you may also experience in your everyday clinical practice. Unfortunately, knowledge about the mechanisms of this metastasis and the options for treatment are still very limited. The BMBC (Brain Metastases in Breast Cancer Network Germany) registry study is therefore intended to contribute to the prospective and retrospective collection of data on the course of disease in patients with brain metastases from breast cancer in order to gain a better understanding of the biology of cerebral metastasis. The aim of the registry study is, among other things, to record the occurrence, diagnosis and treatment of brain metastases. In addition, scientific projects are planned that will contribute to a better understanding of the causes of the development of brain metastases in breast cancer by examining existing kerosene tissue. This should improve the treatment of our patients in the future.

The registry is run in cooperation with the Department of Gynecology at the University Medical Center Hamburg-Eppendorf, AGO-Trafo, AGO-B and the GBG. The documentation effort is manageable and comparable to the "Breast cancer in pregnancy" register, which you may already be familiar with.

If you are interested in participating in the register study and would like to support the project, please contact

• BrainMet@gbg.de or
• Prof. Dr. Volkmar Müller, University Medical Center Hamburg-Eppendorf, E-Mail: v.mueller@uke.de  or 
• PD Dr. Isabell Witzel, University Medical Center Hamburg-Eppendorf, E-Mail: iwitzel@uke.de or 
• Dr. Elena Laakmann, University Medical Center Hamburg-Eppendorf, E-Mail: e.laakmann@uke.de

Thank you for your interest and support!

Study-Status: open

In July 2023 the 4000th patient was recruited. The patient comes from the center Apaglesion Diakonieklinikum Rotenburg Wümme Klinik für Frauenheilkunde und gynäkologische Onkologie, Elise-Averdieck-Strasse 17, 27356 Rotenburg. Many thanks to Dr. Tobias Hesse and Ms. Svenja Behrens and to the entire study team. 

In order to participate in the registry study, an submission for professional advice must be submitted in accordance with §15 of the Professional Code of Conduct. In general, the submission should be accompanied by a formless cover letter, the protocol, the patient consent form and approvals from other ethics committees. The required documents can be found in the "Documents" section. Please note that, depending on the ethics committee, further documents may also be required. Please also note that we cannot cover any costs incurred.

Special regulations apply to the ethics committees of the Bayerischen Landesärztekammer, the Landesärztekammer Baden-Württemberg, the Ärztekammer Berlin and the Ärztekammer Nordrhein. Centers for which one of these ethics committees is responsible should contact the GBG at brainmet@gbg.de.